|
|
(R)-(indol-3-yl)lactate + NAD+ <=> 3-Indole-2-oxopropanoate + NADH + H+
|
1.1.1.110
aromatic 2-oxoacid reductase
|
–
|
BMK
|
|
BRENDA:
BR29176
KEGG:
R12256
MetaCyc:
INDOLELACTATE-DEHYDROGENASE-RXN
|
|
|
|
H+ + 3-Indole-2-oxopropanoate <=> CO2 + Indole-3-acetaldehyde
|
4.1.1.1
pyruvate decarboxylase
4.1.1.43
phenylpyruvate decarboxylase
4.1.1.72
branched-chain-2-oxoacid decarboxylase
4.1.1.74
indolepyruvate decarboxylase
|
–
–
–
–
|
BMK
|
|
BRENDA:
BR335
KEGG:
R01974
MetaCyc:
4.1.1.74-RXN
SABIO-RK:
2017
|
|
|
|
L-tryptophan + H2O + NADP+ <=> 3-Indole-2-oxopropanoate + NH3 + NADPH + H+
|
1.4.1.19
tryptophan dehydrogenase
|
–
|
|
|
BRENDA:
BR36867
KEGG:
R00676
MetaCyc:
TRYPTOPHAN-DEHYDROGENASE-RXN
|
|
|
|
L-tryptophan + H2O + NAD+ <=> 3-Indole-2-oxopropanoate + NH3 + NADH + H+
|
1.4.1.19
tryptophan dehydrogenase
1.4.1.20
phenylalanine dehydrogenase
1.4.1.5
L-amino-acid dehydrogenase
|
–
–
–
|
|
|
BRENDA:
BR36867-a
KEGG:
R00675
MetaCyc:
TRYPTOPHAN-DEHYDROGENASE-RXN_WOP
|
|
|
|
S-adenosyl-L-methionine + 3-Indole-2-oxopropanoate <=> S-adenosyl-L-homocysteine + (R)-3-(indol-3-yl)-2-oxobutanoate + H+
|
2.1.1.47
indolepyruvate C-methyltransferase
|
–
|
M
|
|
BRENDA:
BR40566
KEGG:
R01972
MetaCyc:
RXN-17530
|
|
|
|
L-tryptophan + 2-oxoglutarate <=> 3-Indole-2-oxopropanoate + L-glutamate
|
2.6.1.1
aspartate transaminase
2.6.1.24
diiodotyrosine transaminase
2.6.1.26
thyroid-hormone transaminase
2.6.1.27
tryptophan transaminase
2.6.1.28
tryptophan---phenylpyruvate transaminase
2.6.1.39
2-aminoadipate transaminase
2.6.1.42
branched-chain-amino-acid transaminase
2.6.1.5
tyrosine transaminase
2.6.1.57
aromatic-amino-acid transaminase
2.6.1.7
kynurenine---oxoglutarate transaminase
2.6.1.9
histidinol-phosphate transaminase
|
–
–
–
–
–
–
–
–
–
–
–
|
BMK
|
|
BRENDA:
BR47678
KEGG:
R00684
MetaCyc:
TRYPTOPHAN-AMINOTRANSFERASE-RXN
SABIO-RK:
1064
|
|
|
|
L-tryptophan + phenylpyruvate <=> 3-Indole-2-oxopropanoate + L-phenylalanine
|
2.6.1.28
tryptophan---phenylpyruvate transaminase
2.6.1.57
aromatic-amino-acid transaminase
2.6.1.64
glutamine---phenylpyruvate transaminase
2.6.1.70
aspartate---phenylpyruvate transaminase
2.6.1.99
L-tryptophan---pyruvate aminotransferase
|
–
–
–
–
–
|
BM
|
|
BRENDA:
BR47679
KEGG:
R01376
MetaCyc:
2.6.1.28-RXN
|
|
|
|
3-Indole-2-oxopropanoate + CoA + oxidized_ferredoxin <=> indoleacetyl-CoA + CO2 + reduced_ferredoxin_[iron-sulfur]_cluster + H+
|
1.2.7.7
3-methyl-2-oxobutanoate dehydrogenase (ferredoxin)
1.2.7.8
indolepyruvate ferredoxin oxidoreductase
|
–
–
|
B
|
|
BRENDA:
BR48035
KEGG:
R07161
MetaCyc:
1.2.7.8-RXN
|
|
|
|
3-Indole-2-oxopropanoate + NADPH + O2 + H+ <=> indole-3-acetic_acid + CO2 + NADP+ + H2O
|
1.14.13.168
indole-3-pyruvate monooxygenase
|
–
|
MK
|
|
BRENDA:
BR50263
KEGG:
R10181
MetaCyc:
RXNDQC-2
|
|
|
|
L-tryptophan + pyruvate <=> 3-Indole-2-oxopropanoate + L-alanine
|
2.6.1.28
tryptophan---phenylpyruvate transaminase
2.6.1.44
alanine---glyoxylate transaminase
2.6.1.5
tyrosine transaminase
2.6.1.51
serine---pyruvate transaminase
2.6.1.57
aromatic-amino-acid transaminase
2.6.1.64
glutamine---phenylpyruvate transaminase
2.6.1.99
L-tryptophan---pyruvate aminotransferase
|
–
–
–
–
–
–
–
|
BMK
|
|
BRENDA:
BR50308
KEGG:
R10180
MetaCyc:
RXN-10139
|
|
|
|
L-tryptophan + 4-methylsulfanyl-2-oxobutanoate <=> 3-Indole-2-oxopropanoate + L-methionine
|
2.6.1
2.6.1.27
tryptophan transaminase
2.6.1.57
aromatic-amino-acid transaminase
2.6.1.88
methionine transaminase
2.6.1.99
L-tryptophan---pyruvate aminotransferase
|
–
–
–
–
–
|
K
|
|
BRENDA:
BS353562
KEGG:
R12055
MetaCyc:
RXN-14685
|
|
|
|
L-tryptophan + H2O + O2 <=> 3-Indole-2-oxopropanoate + NH3 + H2O2
|
1.4.3.2
L-amino-acid oxidase
|
–
|
K
|
|
BRENDA:
BS373648
KEGG:
R00677
SABIO-RK:
1057
|
|
|
|
D-tryptophan + H2O + O2 <=> 3-Indole-2-oxopropanoate + NH3 + H2O2
|
1.4.3.3
D-amino-acid oxidase
|
–
|
|
|
BRENDA:
BS259053
SABIO-RK:
11667
|
|
|
|
L-tryptophan + glyoxylate <=> 3-Indole-2-oxopropanoate + glycine
|
2.6.1.27
tryptophan transaminase
2.6.1.44
alanine---glyoxylate transaminase
2.6.1.51
serine---pyruvate transaminase
2.6.1.60
aromatic-amino-acid---glyoxylate transaminase
2.6.1.63
kynurenine---glyoxylate transaminase
2.6.1.7
kynurenine---oxoglutarate transaminase
|
–
–
–
–
–
–
|
|
|
BRENDA:
BS354015
SABIO-RK:
13949
|
|
|
|
S-adenosyl-L-methionine + 3-Indole-2-oxopropanoate <=> S-adenosyl-L-homocysteine + 3-Methylindolepyruvate
|
2.1.1.47
indolepyruvate C-methyltransferase
|
–
|
K
|
|
KEGG:
R01973
|
|
|
|
3-Indole-2-oxopropanoate + ATP <=> didemethylasterriquinone_D + AMP + diphosphate
|
not assigned
|
–
|
M
|
|
MetaCyc:
RXN-15608
|
|
|
|
L-tryptophan + 3-Indole-2-oxopropanoate <=> 3-Indole-2-oxopropanoate + L-tryptophan
|
2.6.1.57
aromatic-amino-acid transaminase
|
–
|
|
|
BRENDA:
BS353557
|
|
|
|
4-hydroxyphenylpyruvate + L-tryptophan <=> L-tyrosine + 3-Indole-2-oxopropanoate
|
2.6.1.28
tryptophan---phenylpyruvate transaminase
2.6.1.57
aromatic-amino-acid transaminase
2.6.1.99
L-tryptophan---pyruvate aminotransferase
|
–
–
–
|
|
|
BRENDA:
BS353555
|
|
|
|
L-leucine + 3-Indole-2-oxopropanoate <=> 4-methyl-2-oxopentanoate + L-tryptophan
|
2.6.1.28
tryptophan---phenylpyruvate transaminase
2.6.1.57
aromatic-amino-acid transaminase
2.6.1.99
L-tryptophan---pyruvate aminotransferase
|
–
–
–
|
|
|
BRENDA:
BS353561
|
|
|
|
L-tryptophan + 2-oxobutyrate <=> 3-Indole-2-oxopropanoate + 2-aminobutanoate
|
2.6.1.28
tryptophan---phenylpyruvate transaminase
2.6.1.7
kynurenine---oxoglutarate transaminase
|
–
–
|
|
|
BRENDA:
BS356432
|
|
|
|
dimethylallyl_diphosphate + 3-Indole-2-oxopropanoate <=> diphosphate + 4-(3-methylbut-2-enyl)-indole-3-pyruvic_acid
|
2.5.1.34
4-dimethylallyltryptophan synthase
|
–
|
|
|
BRENDA:
BS388570
|
|
|
|
dimethylallyl_diphosphate + 3-Indole-2-oxopropanoate <=> diphosphate + 7-(3-methylbut-2-enyl)-indole-3-pyruvic_acid
|
2.5.1.80
7-dimethylallyltryptophan synthase
|
–
|
|
|
BRENDA:
BS397054
|
|
|
|
L-tryptophan + 4-methylsulfanyl-2-oxobutanoate <=> 3-Indole-2-oxopropanoate + 2-aminomethylthiobutanoate
|
2.6.1.27
tryptophan transaminase
|
–
|
|
|
BRENDA:
BS437652
|
|
|
|
prephenate + L-tryptophan <=> 1-Carboxy-4-hydroxy-2,5-cyclohexadien-1-alanine + 3-Indole-2-oxopropanoate
|
2.6.1.57
aromatic-amino-acid transaminase
|
–
|
|
|
BRENDA:
BS353554
|
|
|
|
L-tryptophan + O2 <=> 3-Indole-2-oxopropanoate
|
1.13.11.26
peptide-tryptophan 2,3-dioxygenase
|
–
|
|
|
BRENDA:
BS288932
|
|
|
|
3-Indole-2-oxopropanoate <=> 3-Indole-2-oxopropanoate
|
4.1.1.84
D-dopachrome decarboxylase
|
–
|
|
|
BRENDA:
BS368697
|
|
|
|
L-tryptophan + H2O + 2 cytochrome_b <=> 3-Indole-2-oxopropanoate + NH3 + 2 reduced_cytochrome_b
|
1.4.99.B3
|
–
|
|
|
BRENDA:
BS439693
|
|
|
|
L-tryptophan + O2 <=> 3-Indole-2-oxopropanoate + NH3
|
1.13.12.15
3,4-dihydroxyphenylalanine oxidative deaminase
|
–
|
|
|
BRENDA:
BS397668
|
|
|
|
DL-tryptophan + H2O + O2 <=> 3-Indole-2-oxopropanoate + NH3 + H2O2
|
1.4.3.2
L-amino-acid oxidase
|
–
|
|
|
BRENDA:
BS413364
|
|
|
|
D-tryptophan + H2O + 2,6-dichlorophenolindophenol <=> 3-Indole-2-oxopropanoate + NH3 + reduced_2,6-dichlorophenolindophenol
|
1.4.99.6
D-arginine dehydrogenase
|
–
|
|
|
BRENDA:
BS260517
|
|
|
|
3-Indole-2-oxopropanoate <=> indole-3-acetic_acid + CO2
|
4.1.1.43
phenylpyruvate decarboxylase
|
–
|
|
|
BRENDA:
BS392253
|
|
|
|
3-Indole-2-oxopropanoate + CoA + methyl_viologen <=> indoleacetyl-CoA + CO2 + reduced_methyl_viologen
|
1.2.7.8
indolepyruvate ferredoxin oxidoreductase
|
–
|
|
|
BRENDA:
BS359434
|
|
|
|
3-indolelactate + O2 <=> 3-Indole-2-oxopropanoate + H2O2
|
1.1.3.15
(S)-2-hydroxy-acid oxidase
|
–
|
|
|
BRENDA:
BS257482
|
|
|
|
L-tryptophan + 2-oxoisovalerate <=> 3-Indole-2-oxopropanoate + L-valine
|
2.6.1.28
tryptophan---phenylpyruvate transaminase
2.6.1.99
L-tryptophan---pyruvate aminotransferase
|
–
–
|
|
|
BRENDA:
BS356428
|
|
|
|
3-indolelactate + 2,6-dichlorophenolindophenol <=> 3-Indole-2-oxopropanoate + reduced_2,6-dichlorophenolindophenol
|
1.1.3.15
(S)-2-hydroxy-acid oxidase
|
–
|
|
|
BRENDA:
BS257483
|
|
|
|
2-oxosuccinamic_acid + L-tryptophan <=> L-asparagine + 3-Indole-2-oxopropanoate
|
2.6.1.14
asparagine---oxo-acid transaminase
|
–
|
|
|
BRENDA:
BS354193
|
|
|
|
L-isoleucine + 3-Indole-2-oxopropanoate <=> 3-methyl-2-oxopentanoate + L-tryptophan
|
2.6.1.99
L-tryptophan---pyruvate aminotransferase
|
–
|
|
|
BRENDA:
BS437637
|
|
|
|
D-tryptophan + pyruvate <=> 3-Indole-2-oxopropanoate + D-alanine
|
2.6.1.21
D-amino-acid transaminase
|
–
|
|
|
BRENDA:
BS353667
|
|
|
|
L-histidine + 3-Indole-2-oxopropanoate <=> 3-(1H-imidazol-4-yl)-2-oxopropanoate + L-tryptophan
|
2.6.1.57
aromatic-amino-acid transaminase
|
–
|
|
|
BRENDA:
BS353560
|
|
|
|
3-Indole-2-oxopropanoate + NH3 + NADH <=> L-tryptophan + NADH + H2O
|
1.4.1.20
phenylalanine dehydrogenase
|
–
|
|
|
BRENDA:
BS232361
|
|
|
|
D-tryptophan + 2-oxoglutarate <=> 3-Indole-2-oxopropanoate + D-glutamate
|
2.6.1.21
D-amino-acid transaminase
|
–
|
|
|
BRENDA:
BS353653
|
|
|
|
3-Indole-2-oxopropanoate + reduced_methyl_viologen <=> 2-hydroxy-3-indolylpropionate + methyl_viologen
|
1.1.99.30
2-oxo-acid reductase
|
–
|
|
|
BRENDA:
BS373457
|
|
|
|
S-adenosyl-L-methionine + 3-Indole-2-oxopropanoate <=> S-adenosyl-L-homocysteine + (S)-beta-methylindolepyruvate
|
2.1.1.47
indolepyruvate C-methyltransferase
|
–
|
|
|
BRENDA:
BS289575
|
|
|
|
L-kynurenine + 3-Indole-2-oxopropanoate <=> Kynurenic_acid + L-tryptophan + H2O
|
2.6.1.7
kynurenine---oxoglutarate transaminase
|
–
|
|
|
BRENDA:
BS353511
|
|
|
|
5-Methyltryptophan + 2-oxoglutarate <=> 3-Indole-2-oxopropanoate + L-glutamate
|
2.6.1.57
aromatic-amino-acid transaminase
|
–
|
|
|
BRENDA:
BS353583
|
|
|
|
5-fluoro-L-tryptophan + 2-oxoglutarate <=> 3-Indole-2-oxopropanoate + L-glutamate
|
2.6.1.57
aromatic-amino-acid transaminase
|
–
|
|
|
BRENDA:
BS353582
|
|
|
|
D-tryptophan + 2-oxoglutarate <=> L-glutamate + 3-Indole-2-oxopropanoate
|
2.6.1.27
tryptophan transaminase
|
–
|
|
|
BRENDA:
BS356408
|
|
|
|
3-indolelactate + NAD+ <=> 3-Indole-2-oxopropanoate + NADH
|
1.1.1.110
aromatic 2-oxoacid reductase
1.1.1.96
diiodophenylpyruvate reductase
|
–
–
|
|
|
BRENDA:
BS186996
|
|
|
|
D-tryptophan + H2O + methylene_blue <=> 3-Indole-2-oxopropanoate + NH3 + reduced_methylene_blue
|
1.4.99.6
D-arginine dehydrogenase
|
–
|
|
|
BRENDA:
BS260538
|
|
|
|
3-Indole-2-oxopropanoate + reduced_benzyl_viologen <=> 2-hydroxy-3-indolylpropionate + Oxidized_benzyl_viologen
|
1.1.99.30
2-oxo-acid reductase
|
–
|
|
|
BRENDA:
BS373456
|
|
|
|
L-tryptophan + 2-Oxopentanoate <=> 3-Indole-2-oxopropanoate + L-norvaline
|
2.6.1.28
tryptophan---phenylpyruvate transaminase
|
–
|
|
|
BRENDA:
BS356431
|
|
|
|
3-Indole-2-oxopropanoate + NADPH <=> 3-indolelactate + NADP+
|
1.1.1.110
aromatic 2-oxoacid reductase
|
–
|
|
|
BRENDA:
BS187841
|
|
|
|
L-tryptophan + 2-Oxohexanoate <=> 3-Indole-2-oxopropanoate + L-norleucine
|
2.6.1.28
tryptophan---phenylpyruvate transaminase
|
–
|
|
|
BRENDA:
BS356429
|
|
|
|
D-tryptophan + oxidized_2,6-dichlorophenolindophenol + H2O <=> 3-Indole-2-oxopropanoate + NH3 + reduced_2,6-dichlorophenolindophenol
|
1.5.99.13
D-proline dehydrogenase
|
–
|
|
|
BRENDA:
BS404921
|
|
|
|
D-tryptophan + 2-oxoadipate <=> 3-Indole-2-oxopropanoate + 2-Aminoadipate
|
2.6.1.74
cephalosporin-C transaminase
|
–
|
|
|
BRENDA:
BS356889
|
|
|
|
L-tryptophan + oxaloacetate <=> 3-Indole-2-oxopropanoate + glycine
|
2.6.1.5
tyrosine transaminase
|
–
|
|
|
BRENDA:
BS423786
|
|
|
|
L-arogenate + 3-Indole-2-oxopropanoate <=> L-tryptophan + 3-(1-carboxy-4-hydroxycyclohexa-2,5-dienyl)2-oxopropanoate
|
2.6.1.57
aromatic-amino-acid transaminase
|
–
|
|
|
BRENDA:
BS353559
|
|
|
|
3-Indole-2-oxopropanoate + acetaldehyde <=> 3-hydroxy-1-(3-indoyl)-2-butanone
|
4.1.1.43
phenylpyruvate decarboxylase
|
–
|
|
|
BRENDA:
BS367950
|
|
|
|
3-Indole-2-oxopropanoate + L-aspartate <=> oxaloaspartate + L-tryptophan
|
2.6.1.70
aspartate---phenylpyruvate transaminase
|
–
|
|
|
BRENDA:
BS356862
|
|
|
|
L-tryptophan + oxaloacetate <=> 3-Indole-2-oxopropanoate + L-aspartate
|
2.6.1.27
tryptophan transaminase
2.6.1.57
aromatic-amino-acid transaminase
2.6.1.70
aspartate---phenylpyruvate transaminase
2.6.1.78
aspartate---prephenate aminotransferase
|
–
–
–
–
|
|
|
BRENDA:
BS353544
|
|
|
|
L-glutamine + 3-Indole-2-oxopropanoate <=> 2-Oxoglutaramate + L-tryptophan
|
2.6.1.57
aromatic-amino-acid transaminase
2.6.1.64
glutamine---phenylpyruvate transaminase
|
–
–
|
|
|
BRENDA:
BS353563
|
|
|
|
D-tryptophan + pyruvate <=> 3-Indole-2-oxopropanoate + L-alanine
|
2.6.1.27
tryptophan transaminase
|
–
|
|
|
BRENDA:
BS356409
|
|
|
|
3-indolelactate + FMN <=> 3-Indole-2-oxopropanoate + FMNH2
|
1.1.99.31
(S)-mandelate dehydrogenase
|
–
|
|
|
SABIO-RK:
6589
|
|
|
|
pyridoxal_5'-phosphate + L-tryptophan <=> pyridoxamine_5'-phosphate + 3-Indole-2-oxopropanoate
|
not assigned
|
–
|
|
|
SABIO-RK:
14607
|
|
|
|
2 3-Indole-2-oxopropanoate <=> didemethylasterriquinone_D
|
not assigned
|
–
|
|
|
SABIO-RK:
14608
|
|